Sandquist G M, Olsen D B, Kolff W J
Ann Biomed Eng. 1982;10(1):1-33. doi: 10.1007/BF02584212.
Beginning with a set of simplifying assumptions and the statements for the hydrodynamic and thermodynamic processes involved, a comprehensive mathematical model for the mammalian circulatory system is developed and evaluated. Analytical relationships are derived and examined for the circulatory component pressures, flow rates, blood volumes, flow resistances, pumping power and pumping rate. The essential circulatory model parameters are identified and inspected for their influence upon circulatory behavior. A complete and consistent set of circulatory model parameters is given for the adult human male and the model response is examined. In general, agreement of the model predictions for man with experimental data is good.
从一组简化假设以及所涉及的流体动力学和热力学过程的陈述出发,开发并评估了一个用于哺乳动物循环系统的综合数学模型。推导并研究了循环系统各组成部分的压力、流量、血容量、流动阻力、泵浦功率和泵浦速率之间的解析关系。确定了循环模型的基本参数,并检查了它们对循环行为的影响。给出了成年男性完整且一致的循环模型参数集,并研究了模型的响应。总体而言,该模型对人体的预测与实验数据吻合良好。