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日本青年人群中的胃癌

Gastric carcinoma in young adults in Japan.

作者信息

Umeyama K, Sowa M, Kamino K, Kato Y, Satake K

出版信息

Anticancer Res. 1982 Sep-Oct;2(5):283-6.

PMID:7165284
Abstract

Forty-nine cases of young adults with carcinoma of the stomach were reviewed. The occurrence of this tumor had a percentage rate of 2.7 of the total of 1767 Japanese patients with stomach carcinoma, with a male to female ratio of 1.0:0.88. The most common complaint observed was epigastric pain (45.7%). In the majority of patients, the period from the onset of symptoms to the time of diagnosis was over two years (49%). Thirty-nine out of 49 patients had resection of the stomach and a consequent operation was curative in 55.1% of them. The overall 5-year survival rate was 26.8%. However, the 5-year survival rate for the curative operation was 42.6% particularly in early gastric carcinoma without any serosal invasion and no patients died from carcinoma of the stomach. These results indicate that early diagnosis is very important to improve the curing rate of this disease in young adults.

摘要

回顾了49例青年胃癌患者。该肿瘤在1767例日本胃癌患者中的发生率为2.7%,男女比例为1.0:0.88。最常见的主诉是上腹部疼痛(45.7%)。大多数患者从症状出现到诊断的时间超过两年(49%)。49例患者中有39例行胃切除术,其中55.1%的患者手术治愈。总体5年生存率为26.8%。然而,根治性手术的5年生存率为42.6%,尤其是早期胃癌且无浆膜侵犯的患者,没有患者死于胃癌。这些结果表明,早期诊断对于提高青年胃癌患者的治愈率非常重要。

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Progesterone enhancement of stomach tumor development in SD rats treated with N-methyl-N'-nitro-N-nitrosoguanidine.孕酮对用N-甲基-N'-硝基-N-亚硝基胍处理的SD大鼠胃肿瘤发展的促进作用。
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