Shea C R, Parrish J A
Arch Dermatol Res. 1982;273(3-4):233-9. doi: 10.1007/BF00409251.
Convective cooling of human skin to 20 degrees C or less for 1 h immediately after ultraviolet-B irradiation (UV-B, 290-320 nm) results in a significant increase in erythemal threshold when erythema was observed at 4-6 h postirradiation. Cooling the skin immediately before UV-B irradiation showed no consistent influence on the erythema response. In neither case was an effect of cooling on erythemal threshold apparent when erythema was evaluated at 24 h postirradiation. These effects may be due to alterations in the diffusion kinetics of chemical mediators of inflammation, modification of vascular responsiveness, or reflect changes in temperature-dependent cellular repair or expression of UV-induced damage.
在紫外线B（UV-B，290 - 320纳米）照射后立即将人体皮肤对流冷却至20摄氏度或更低并持续1小时，当在照射后4 - 6小时观察到红斑时，红斑阈值会显著增加。在UV-B照射前立即冷却皮肤对红斑反应没有一致的影响。在这两种情况下，当在照射后24小时评估红斑时，冷却对红斑阈值的影响均不明显。这些影响可能是由于炎症化学介质扩散动力学的改变、血管反应性的改变，或反映了温度依赖性细胞修复的变化或紫外线诱导损伤的表达变化。
