Antsaklis A, Aravantinos D, Kaskarelis D
Clin Exp Obstet Gynecol. 1982;9(3):189-92.
The authors evaluate the efficacy and safety of fetoscopy on a series of 510 patients in which the procedure was carried out between the 18th and 20th week of gestation in order to obtain a suitable fetal blood sample for prenatal genetic diagnosis; the whole pregnancy could be completely followed up in them. The complication rate was low (1.7%) when the first attempt of fetoscopy was successful, but rose dramatically up to 17.9% on repeated attempts: however, they only amounted to 7.8% of all cases. The results of their study lead the authors to propose fetoscopy as a powerful, accurate and safe addition to the presently available diagnostic methods, provided it is performed by well trained fetoscopists, under aseptic conditions and local anaesthesia.
作者评估了胎儿镜检查对510例患者的有效性和安全性。这些患者在妊娠第18至20周期间接受了该检查，目的是获取合适的胎儿血样用于产前基因诊断；所有这些患者的整个孕期都得到了完整的随访。首次胎儿镜检查成功时并发症发生率较低（1.7%），但重复检查时并发症发生率急剧上升至17.9%：不过，这些并发症仅占所有病例的7.8%。他们的研究结果使作者提出，只要由训练有素的胎儿镜检查医生在无菌条件和局部麻醉下进行，胎儿镜检查可作为现有诊断方法的一种强大、准确且安全的补充手段。
