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用异戊巴比妥后听觉不对称性的变化:脑药理学不对称性的证据?

Change in auditory asymmetry with amobarbital: evidence of cerebral pharmacological asymmetry?

作者信息

Frumkin L R, Ward N G, Grim P S, Burke P, Chen A, Ripley H S

出版信息

Int J Neurosci. 1982 Jul;17(1):1-7. doi: 10.3109/00207458208985081.

DOI:10.3109/00207458208985081
PMID:7166468
Abstract

Eleven right-handed subjects were administered a dichotic listening test to assess cerebral hemispheric dominance, both under a drug-free condition and following systemic injection of the barbiturate, amobarbital. The finding of increased right ear advantage during the drug period reflects increased left cerebral dominance, and suggests that amobarbital may have an asymmetric, pharmacological effect on the two cerebral hemispheres.

摘要

11名右利手受试者接受了一项双耳分听测试,以评估大脑半球优势,测试分别在无药物状态下以及全身注射巴比妥酸盐异戊巴比妥之后进行。发现在用药期间右耳优势增加,这反映出左脑优势增强,表明异戊巴比妥可能对两个大脑半球具有不对称的药理作用。

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