Hollender L F, Meyer C
Zentralbl Chir. 1978;103(19):1256-63.
147 cases of carcinoma of the pancreas are presented excluding cancer of the ampulla and endocrine tumours. Only 21 (14,9%) radical pancreatectomies could be performed with 3 deaths. 83 (56,4%) patients were treated by palliative procedures with 16,8% deaths. 21 (14,9%) patients had explorative laparotomy with a 27,2% mortality rate. The mean survival time is 11,5 months after duodeno-pancreatico-resection and 16 months after total pancreatectomy. The mean survival time in palliative surgery is 14,8 months. There was no survival at all after 5 years. Our surgical indication depends on local extension, but above all on lymphnode metastases: if there are more than 3 metastased nodes in the frozen section, radical surgery seems to be useless. On the other hand, total pancreatectomy gives better results for morbidity, operative mortality and survival rates than segmental resection.
本文呈现了147例胰腺癌病例，不包括壶腹癌和内分泌肿瘤。仅21例（14.9%）患者接受了根治性胰切除术，其中3例死亡。83例（56.4%）患者接受了姑息性手术，死亡率为16.8%。21例（14.9%）患者接受了剖腹探查术，死亡率为27.2%。十二指肠-胰切除术术后平均生存时间为11.5个月，全胰切除术后为16个月。姑息性手术的平均生存时间为14.8个月。5年后无一例存活。我们的手术指征取决于局部扩展情况，但最重要的是取决于淋巴结转移情况：如果冰冻切片中有超过3个转移淋巴结，根治性手术似乎毫无意义。另一方面，与节段性切除相比，全胰切除术在发病率、手术死亡率和生存率方面效果更好。
