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[大鼠骨骼肌离子组成与功能活性之间的关系]

[Relationship between the ionic composition and functional activity of rat skeletal muscles].

作者信息

Nesterov V P

出版信息

Zh Evol Biokhim Fiziol. 1978 Sep-Oct;14(5):453-60.

PMID:716707
Abstract

Studies have been made on the relationship between the pattern of distribution of sodium and potassium ions in skeletal muscles of rats (tissue concentrations of ions, ionic selectivity of the tissue) and the level of functional activity of these muscles under experimental influences upon the motor system of the animals. It was shown that prolonged (20 days) effect of weightlessness during a cosmic flight (functional unloading of the motor apparatus) induces changes in tissue concentrations of Na+ and K+ (the increase of the former and the decrease of the latter) only in postural-tonic m. soleus, which accounts for antigravitational function in the organism. In m. phrenicus and m. plantaris no significant shifts in tissue concentrations of ions were detected. severe hypokinesia (30 days) in the laboratory, as well as denervation (30 days) considerably decrease tissue concentrations of K+ and increase that of Na+ in fast skeletal muscles; under the same conditions, slow m. soleus exhibits simultaneous changes in tissue concentrations of Na+ and K+, although these are less significant.

摘要

已经对大鼠骨骼肌中钠和钾离子的分布模式(离子的组织浓度、组织的离子选择性)与在对动物运动系统进行实验性影响时这些肌肉的功能活动水平之间的关系进行了研究。结果表明,宇宙飞行期间失重的长期(20天)影响(运动装置的功能卸载)仅在机体中具有抗重力功能的姿势紧张性比目鱼肌中引起Na+和K+组织浓度的变化(前者增加而后者减少)。在膈肌和跖肌中未检测到离子组织浓度的显著变化。实验室中的严重运动不足(30天)以及去神经支配(30天)会显著降低快速骨骼肌中K+的组织浓度并增加Na+的组织浓度;在相同条件下,慢速比目鱼肌中Na+和K+的组织浓度同时发生变化,尽管这些变化不太明显。

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1
[Relationship between the ionic composition and functional activity of rat skeletal muscles].[大鼠骨骼肌离子组成与功能活性之间的关系]
Zh Evol Biokhim Fiziol. 1978 Sep-Oct;14(5):453-60.
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