Nesterov V P, Tigranian R A
Kosm Biol Aviakosm Med. 1979 Jul-Aug;13(4):26-30.
Measurements of Na+, K+, Mg2+ and Ca2+ concentrations in the functionally different muscles (soleus, plantaris, diaphragm muscles) and plasma of the rats flown for 20.5 days aboard the biosatellite Cosmos-690 did not show any significant changes as compared with the controls. At the same time a decrease of the K+/Na+ ratio and a similar shift of Mg2+ and Ca2+ concentrations in plasma of irradiated rats as compared with these of non-irradiated animals demonstrated that the combined effects of space flight factors and gamma-irradiation influenced the system of ionic homeostasis in the blood. In the animals sacrificed on the R + 1 day the K+/Na+ ratio in the soleus muscle changed in favor of Na+ and in the plantaris muscle in favor of K+, and remained essentially unchanged in the diaphragm. The comparison of the flight experiments with the ground-based controls showed that ion changes in muscles occurred due to ionizing radiation rather than due to weightlessness.
对搭载在生物卫星“宇宙-690”号上飞行20.5天的大鼠的功能不同的肌肉(比目鱼肌、跖肌、膈肌)和血浆中的Na+、K+、Mg2+和Ca2+浓度进行测量,结果显示与对照组相比没有任何显著变化。与此同时,与未受辐照动物相比,受辐照大鼠血浆中K+/Na+比值降低,Mg2+和Ca2+浓度也有类似变化,这表明太空飞行因素和γ射线辐照的综合作用影响了血液中的离子稳态系统。在辐照后第1天处死的动物中,比目鱼肌中的K+/Na+比值向有利于Na+的方向变化,跖肌中的比值向有利于K+的方向变化,而膈肌中的比值基本保持不变。将飞行实验与地面对照组进行比较表明,肌肉中的离子变化是由电离辐射而非失重引起的。