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[癫痫发作激活期癫痫患者脑血流灌注动力学]

[Dynamics of cerebral blood filling in epileptic patients during seizure activation].

作者信息

Beĭn B N, Shatokhin V M

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1978 Sep-Oct(5):21-6.

PMID:716745
Abstract

The interrelationship of cerebral hemodynamics and cerebral vascular tonus was studied in 36 patients with epilepsy during activation of discharges and provocation of epileptic seizures by hyperventilation and intravenous corazol infusion by simultaneous EEG and REG recording. It was found that regional functional hyperemia in the brain corresponding to the side of the epileptogenic focus increases during activation of the discharges despite a certain increase in the tonus of the cerebral vessels. During and immediately after an epileptic seizure angiospasm is replaced by vasodilation with further growth in blood filling of the brain. The possible mechanisms of the vascular reaction are discussed.

摘要

通过同步脑电图(EEG)和脑电阻抗图(REG)记录,对36例癫痫患者在放电激活以及通过过度换气和静脉注射戊四氮诱发癫痫发作期间的脑血流动力学与脑血管张力的相互关系进行了研究。结果发现,尽管脑血管张力有一定增加,但在放电激活期间,对应于致痫灶一侧的大脑局部功能性充血仍会增加。癫痫发作期间及发作后即刻,血管痉挛被血管扩张所取代,脑血流量进一步增加。文中讨论了血管反应的可能机制。

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