Kohlmeyer K
Z Gerontol. 1982 Nov-Dec;15(6):321-4.
Studies of computed tomography were performed in 367 patients diagnosed as dementia clinically. The mean age was 70.1 years. By the clinicians 240 were classified as senile dementia of Alzheimer's type, 79 as multiinfarct dementia, and 48 were not determined definitely. In 3%, the CT studies did detect treatable causes like tumors, subdural hematomas and communicating hydrocephalus. In about 57% was found by CT a diffuse brain atrophy without focal tissue changes as to expect if occurring a cerebrovascular disease. In 25% there were focal changes of the brain tissue in CT to define as residuals of infarctions in addition to the signs of cerebral atrophy. The results of the CT studies were normal in 15% despite of the evidence of dementia clinically. The analysis of the material did show that a cerebrovascular disease as a cause of dementia is suspected clinically in much more cases than CT studies are able to prove focal pathological changes of the brain tissue due to disorders of cerebral blood flow really.
对367例临床诊断为痴呆的患者进行了计算机断层扫描研究。平均年龄为70.1岁。临床医生将240例归类为阿尔茨海默型老年痴呆,79例归类为多发性梗死性痴呆,48例未明确诊断。在3%的患者中,CT检查确实发现了可治疗的病因,如肿瘤、硬膜下血肿和交通性脑积水。在约57%的患者中,CT发现弥漫性脑萎缩,无局灶性组织改变,这与发生脑血管疾病时预期的情况一致。在25%的患者中,CT显示脑组织有局灶性改变,除脑萎缩迹象外,还可定义为梗死灶残留。尽管临床有痴呆证据,但15%的患者CT检查结果正常。对资料的分析表明,临床上怀疑为脑血管疾病所致痴呆的病例比CT研究能够证实因脑血流紊乱导致脑组织局灶性病理改变的病例多得多。