Erkinjuntti T, Ketonen L, Sulkava R, Vuorialho M, Palo J
Acta Neurol Scand. 1987 Apr;75(4):262-70. doi: 10.1111/j.1600-0404.1987.tb07931.x.
A prospective series of consecutively admitted patients with Alzheimer's disease (AD) (n = 68), multi-infarct dementia (MID) (n = 79) and probable vascular dementia (PVD) (n = 46) were studied by CT of the head. In MID 88.6% and in PVD 41.3% of the patients had at least one brain infarct on CT, but only one patient (1.5%) with AD. White matter low attenuation (WMLA) also differentiated MID and PVD from AD, especially among patients aged 75 years or less, and with mild or moderate dementia. In all types, brain atrophy on CT had a positive correlation with the degree of dementia. Infarcts and WMLA on CT, but not brain atrophy seem to be of differential diagnostic value between vascular and degenerative dementia.
对一系列前瞻性连续收治的阿尔茨海默病（AD）患者（n = 68）、多发梗死性痴呆（MID）患者（n = 79）和可能的血管性痴呆（PVD）患者（n = 46）进行了头部CT研究。在MID患者中，88.6%的患者CT显示至少有一处脑梗死，PVD患者中这一比例为41.3%，而AD患者中只有1例（1.5%）有脑梗死。白质低密度（WMLA）也可将MID和PVD与AD区分开来，尤其是在75岁及以下、患有轻度或中度痴呆的患者中。在所有类型中，CT上的脑萎缩与痴呆程度呈正相关。CT上的梗死灶和WMLA，而非脑萎缩，似乎在血管性痴呆和退行性痴呆之间具有鉴别诊断价值。
