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双眼剥夺猫皮层对模式刺激的视觉诱发电位

Visually evoked potentials to pattern stimuli in cortex of binocularly deprived cats.

作者信息

Sobótka S, Javrishvili T, Radil T, Zernicki B

出版信息

Acta Neurobiol Exp (Wars). 1982;42(2):135-49.

PMID:7168375
Abstract

Visually evoked potentials (VEPs) were compared in 7 normally reared cats (N cats) and 9 cats deprived of pattern vision during postnatal period. In 4 deprived cats (D cats) recording was done immediately after deprivation period which lasted from 6 to 24 months. In 5 cats (DE cats) 6 months of deprivation was followed by 4-18 months of visual experience. Two stimuli were used: a large stationary stimulus (a 30 per 30 degrees grating pattern illuminated by flash) and a small moving stimulus (a smaller grating pattern was located in different parts of visual field and illuminated by a moving 1 per 4 degrees light slit). The VEPs were recorded in the marginal, suprasylvian, ectosylvian and sigmoid gyri. As compared with N cats, in D cats the VEPs in all cortical areas were of simpler form, more variable and of greater amplitude. Moreover, in contrast to N cats, in D cats the VEPs were of similar amplitude when evoked from the contra or homolateral visual field. However, results in DE cats showed that these changes are largely reversible.

摘要

对7只正常饲养的猫(N组猫)和9只在出生后被剥夺模式视觉的猫的视觉诱发电位(VEP)进行了比较。在4只剥夺视觉的猫(D组猫)中,剥夺期持续6至24个月,剥夺期结束后立即进行记录。在5只猫(DE组猫)中,先剥夺视觉6个月,然后给予4至18个月的视觉体验。使用了两种刺激:一种是大的静止刺激(一个30×30度的光栅图案,由闪光灯照亮)和一种小的移动刺激(一个较小的光栅图案位于视野的不同部位,由一个每4度移动一次的1度光缝照亮)。在边缘回、上薛氏回、外薛氏回和乙状回记录VEP。与N组猫相比,D组猫所有皮质区域的VEP形式更简单、更易变且振幅更大。此外,与N组猫不同的是,D组猫从对侧或同侧视野诱发的VEP振幅相似。然而,DE组猫的结果表明,这些变化在很大程度上是可逆的。

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