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长期单眼剥夺猫的视网膜电图和视觉诱发电位

Electroretinograms and visual evoked potentials in long-term monocularly deprived cats.

作者信息

Baro J A, Lehmkuhle S, Kratz K E

机构信息

School of Optometry, University of Missouri-St. Louis 63121.

出版信息

Invest Ophthalmol Vis Sci. 1990 Jul;31(7):1405-9.

PMID:2365572
Abstract

The effects of long-term monocular lid-suture deprivation on visual-evoked cortical potentials (VEPs) and flash- and pattern-evoked electroretinograms (FERGs and PERGs, respectively) were assessed in the cat. VEPs were virtually eliminated when recorded with the deprived eye, indicating that the lid suture produced a severe amblyopia in that eye. In contrast, FERGs and PERGs were more similar for both deprived and nondeprived eyes and comparable to those recorded in normal animals. The current findings demonstrate that long-term deprivation (3-4 yr) does not produce systematic changes in the electroretinogram.

摘要

在猫身上评估了长期单眼眼睑缝合剥夺对视诱发电位(VEP)以及闪光诱发和图形诱发视网膜电图(分别为FERG和PERG)的影响。用被剥夺的眼睛记录时,VEP几乎消失,这表明眼睑缝合在该眼产生了严重的弱视。相比之下,剥夺眼和未剥夺眼的FERG和PERG更为相似,且与正常动物记录的结果相当。目前的研究结果表明,长期剥夺(3 - 4年)不会使视网膜电图产生系统性变化。

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