Gupta S, Verma S R, Saxena P K
Ecotoxicol Environ Saf. 1982 Oct;6(5):433-8. doi: 10.1016/0147-6513(82)90023-9.
Fish, Notopterus notopterus, in four sizes (4.5 +/- 1.0, 9.0 +/- 1.0, 14.5 +/- 1.2, and 22.6 +/- 1.8 cm in length) were exposed to phenol (P), 2,4-dinitrophenol (DNP), and pentachlorophenol (PCP) separately, and also to their three combinations (PCP + DNP)/P (highly antagonistic), (DNP + P)/PCP (additive), and (P + DNP)/PCP (highly synergistic) to evaluate the effect of fish size on the toxicity of these chemicals separately and in combination. The results reveal that with increased fish size (from 4.5 + 1.0 to 14.5 + 12 cm in length) toxicity of phenolic compounds decreased. On the contrary, the larger size fish (22.6 +/- 1.8 cm in length) was comparatively more susceptible. This indicates that change in fish size does influence the toxicity of phenolic compounds.
将四种不同大小（体长分别为4.5±1.0、9.0±1.0、14.5±1.2和22.6±1.8厘米）的背眼弓背鱼分别暴露于苯酚（P）、2,4-二硝基苯酚（DNP）和五氯苯酚（PCP）中，同时也暴露于它们的三种组合中，即（PCP + DNP）/P（高度拮抗）、（DNP + P）/PCP（相加）和（P + DNP）/PCP（高度协同），以评估鱼的大小对这些化学物质单独及组合毒性的影响。结果表明，随着鱼体大小的增加（体长从4.5 + 1.0厘米增加到14.5 + 1.2厘米），酚类化合物的毒性降低。相反，较大尺寸的鱼（体长22.6±1.8厘米）相对更敏感。这表明鱼大小的变化确实会影响酚类化合物的毒性。
