Lindner J
Langenbecks Arch Chir. 1982;358:153-60. doi: 10.1007/BF01271773.
Wound healing was investigated by morphological and biochemical methods. The results show that wounds cause disturbances in the equilibrium between the physiological anabolic and catabolic processes of cells, ground substance, and fibers (with increased turnover rates). The primary increase of catabolism is responsible for the secondary compensatory enhanced anabolism, especially of proteoglycans and collagen. Kind, size, and localization of wounds determine the course of wound healing and therefore the extent of adaptation of structure, function, and biomechanical capacities on the surrounding uninjured tissue.
通过形态学和生物化学方法对伤口愈合进行了研究。结果表明，伤口会导致细胞、基质和纤维的生理合成代谢与分解代谢过程之间的平衡失调（周转率增加）。分解代谢的最初增加导致了继发性代偿性合成代谢增强，尤其是蛋白聚糖和胶原蛋白的合成代谢增强。伤口的种类、大小和位置决定了伤口愈合的过程，从而也决定了周围未受伤组织在结构、功能和生物力学能力方面的适应程度。
