Decaux G, Van Laethem Y, Van Kuyck M, Mockel J
Miner Electrolyte Metab. 1982 Apr;7(4):192-6.
Mild hypocalcemia was observed in 6 out of 12 patients with SIADH associated hyponatremia, this was in fact related to low albumin levels resulting partly from body fluid dilution. In the 7 SIADH patients where it was measured, we observed an increased fractional calcium excretion (3.2 +/- 1.7%) as long as the patients were hyponatremic. This was corrected by water restriction (0.73 +/- 0.4%, p less than 0.01). We suggest that volume expansion was responsible for the increased calcium clearance, and not hyponatremia by itself, since in volume depletion hyponatremia, calcium clearance was within the normal range. Mild hypocalcemia and hypercalciuria is a common finding in SIADH-associated hyponatremia.
在12例抗利尿激素分泌异常综合征（SIADH）伴低钠血症患者中，有6例出现轻度低钙血症，这实际上与体液稀释导致的白蛋白水平降低有关。在7例接受检测的SIADH患者中，我们观察到，只要患者处于低钠血症状态，其钙排泄分数就会增加（3.2±1.7%）。通过限水，这一情况得到纠正（0.73±0.4%，p<0.01）。我们认为，容量扩张是导致钙清除率增加的原因，而非低钠血症本身，因为在容量减少性低钠血症中，钙清除率处于正常范围。轻度低钙血症和高钙尿症是SIADH伴低钠血症的常见表现。
