Johansen K, Hansen J M, Skovsted L
Acta Med Scand. 1978;204(5):357-9. doi: 10.1111/j.0954-6820.1978.tb08454.x.
The free triiodothyronine index (FT3I) was significantly correlated to basal metabolic rate (BMR) in hyperthyroid (r=+0.63, p less than 0.01) and hypothyroid patients (r=+0.61, p less than 0.05). Elimination of the effect of the free thyroxine index (FT4I) on the total correlation between BMR and FT3I by partial correlation analysis gave partial r=+0.60, p less than 0.01 in hyperthyroid patients and partial r=+0.43, p less than 0.1 in hypothyroid patients. The FT4I did not correlate to BMR in either hyper- or hypothyroid patients. These results point to triiodothyronine as the major regulator of BMR in hyper- and hypothyroidism.
在甲状腺功能亢进患者中,游离三碘甲状腺原氨酸指数(FT3I)与基础代谢率(BMR)显著相关(r = +0.63,p < 0.01);在甲状腺功能减退患者中,二者也显著相关(r = +0.61,p < 0.05)。通过偏相关分析消除游离甲状腺素指数(FT4I)对BMR与FT3I之间总相关性的影响后,在甲状腺功能亢进患者中得到的偏相关系数r = +0.60,p < 0.01;在甲状腺功能减退患者中,偏相关系数r = +0.43,p < 0.1。在甲状腺功能亢进或减退患者中,FT4I与BMR均无相关性。这些结果表明,在甲状腺功能亢进和减退状态下,三碘甲状腺原氨酸是BMR的主要调节因子。