Meola S M, Rowe L D, Lovering S L, Moore E G
Scan Electron Microsc. 1982(Pt 3):1229-35.
Scanning electron microscopy, correlated with hematological and clinical biochemical observations demonstrated that cytoplasmic bridges develop between the erythrocytes of sheep in which varying degrees of acute renal dysfunction has been produced by treatment with a toxin (uranyl nitrate) or by surgical ligation of a renal artery or ureter. The presence of cytoplasmic bridges between red blood cells was noted prior to clinical indication of renal dysfunction. Thus, these preliminary studies indicate that the development of cytoplasmic bridges between erythrocytes may be a diagnostic clue for early detection of renal dysfunction.
扫描电子显微镜检查结合血液学和临床生化观察表明，在用毒素（硝酸铀酰）处理或通过手术结扎肾动脉或输尿管导致不同程度急性肾功能障碍的绵羊红细胞之间会形成细胞质桥。在肾功能障碍出现临床指征之前，就已注意到红细胞之间存在细胞质桥。因此，这些初步研究表明，红细胞之间细胞质桥的形成可能是早期检测肾功能障碍的一个诊断线索。
