Alcantara A K, Buck R L, Uylangco C V, Cross J H
Southeast Asian J Trop Med Public Health. 1982 Dec;13(4):563-7.
Forty cases of cerebral Plasmodium falciparum malaria seen at San Lazaro Hospital, Manila, Philippines from 1979-1981 were reviewed. These cases represented 7% of all Plasmodium falciparum cases seen during this period. All of the patients had fever and headache, 73% confusion, 70% chills, 68% jaundice or abdominal pain, 60% sweats. Findings more frequent in the fatal compared to the non-fatal cases were: the presence of schizonts in the peripheral smear, oliguria, coma, convulsions, urinary incontinence, jaundice, pulmonary symptoms and vomiting. Fatal cases were less likely to be clinically diagnosed as malaria and more likely to be diagnosed as hepatitis than malaria. The treatment and management of these cases is discussed.
回顾了1979年至1981年期间在菲律宾马尼拉圣拉萨罗医院所见的40例脑型恶性疟病例。这些病例占该时期所有恶性疟病例的7%。所有患者均有发热和头痛，73%有精神错乱，70%有寒战，68%有黄疸或腹痛，60%有出汗。与非致命病例相比，致命病例中更常见的表现有：外周血涂片中有裂殖体、少尿、昏迷、惊厥、尿失禁、黄疸、肺部症状和呕吐。致命病例临床诊断为疟疾的可能性较小，而诊断为肝炎而非疟疾的可能性较大。文中讨论了这些病例的治疗和管理。
