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Thallium intoxication treated with long-term hemodialysis, forced diuresis and Prussian blue.

作者信息

Pedersen R S, Olesen A S, Freund L G, Solgaard P, Larsen E

出版信息

Acta Med Scand. 1978;204(5):429-32. doi: 10.1111/j.0954-6820.1978.tb08467.x.

DOI:10.1111/j.0954-6820.1978.tb08467.x
PMID:717064
Abstract

A 56-year-old woman, who ingested 2 g of thallium sulfate, was successfully treated with long-term hemodialysis for 200 hours during ten days, combined with forced diuresis and Prussian blue. The effect of the artificial kidney dialysis was determined by repeated analysis of the thallium concentration in the dialysis bath and in blood samples. During the first 120 hours of hemodialysis, 143 mg of thallium was eliminated via the artificial kidney and 110 mg via the urinary tract. The present case of acute thallium intoxication is the first in which long-term hemodialysis has been used in the acute phase together with forced diuresis and Prussian blue. The data obtained are compared to those obtained from cases treated with hemodialysis in the past. It is concluded that treatment with hemodialysis should be considered as an important supplement to treatment with forced diuresis and Prussian blue in cases of thallium intoxication.

摘要

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Thallium intoxication treated with long-term hemodialysis, forced diuresis and Prussian blue.
Acta Med Scand. 1978;204(5):429-32. doi: 10.1111/j.0954-6820.1978.tb08467.x.
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引用本文的文献

1
A fatal case of thallium toxicity: challenges in management.铊中毒致死 1 例:诊治难点。
J Med Toxicol. 2013 Mar;9(1):75-8. doi: 10.1007/s13181-012-0251-1.
2
Pharmacokinetic parameters for thallium (I)-ions in man.
Arch Toxicol. 1983 May;53(1):1-7. doi: 10.1007/BF01459996.
3
An evaluation of the efficacy of charcoal haemoperfusion in the treatment of three cases of acute thallium poisoning.炭血液灌注治疗三例急性铊中毒的疗效评估。
Arch Toxicol. 1985 Apr;57(1):61-6. doi: 10.1007/BF00286577.
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Poisoning by thallium. A study of five cases.
Drug Saf. 1990 Sep-Oct;5(5):384-9. doi: 10.2165/00002018-199005050-00006.