De Muylder X, Moutquin J M, Desgranges M F, Leduc B, Lazaro-Lopez F
Acta Genet Med Gemellol (Roma). 1982;31(3-4):149-55. doi: 10.1017/s0001566000008230.
Four hundred and thirty-four twins delivered from 220 women at Notre-Dame Hospital were studied during a period of 11 years (1969-1979). The maternal, fetal, and neonatal outcome was compared before and after 1974, the year ultrasonography and other changes in perinatal care were introduced in our institution. Early diagnosis occurred more frequently after 1974, together with increased antenatal hospitalization. Preeclampsia and hepatic cholestasis occurred in 19.5% and 9.5% of women, respectively. Preterm delivery occurred in 42.2% of the cases. The corrected fetal mortality rate was 30.2/1,000 and corrected perinatal mortality rate was 74.9/1,000. About 90% of the neonatal deaths occurred in infants born before 36 weeks. Internal version and complete extraction of the second twin increased the neonatal mortality sixfold compared to spontaneous delivery. Availability of ultrasound examination significantly reduced preterm delivery.
在11年期间（1969 - 1979年），对圣母医院220名产妇所分娩的434对双胞胎进行了研究。对1974年前后的孕产妇、胎儿及新生儿结局进行了比较，1974年是我院引入超声检查及围产期护理其他变革的年份。1974年之后早期诊断更为频繁，同时产前住院率增加。子痫前期和肝内胆汁淤积症分别发生在19.5%和9.5%的产妇中。42.2%的病例发生早产。校正后的胎儿死亡率为30.2/1000，校正后的围产期死亡率为74.9/1000。约90%的新生儿死亡发生在孕36周前出生的婴儿中。与自然分娩相比，内倒转术及第二个胎儿的完全娩出使新生儿死亡率增加了六倍。超声检查的应用显著降低了早产率。
