Blika S, Saunte E
Acta Ophthalmol (Copenh). 1982 Dec;60(6):967-76. doi: 10.1111/j.1755-3768.1982.tb00629.x.
180 eyes of 97 patients with primary open angle glaucoma and IOP greater than 22 mm were treated for more than 3 years with timolol-maleate. 130 eyes had glaucoma simplex, and 50 eyes had glaucoma capsulare. With timolol maleate as the only medication after 3 years, the IOP was controlled in 33% of the glaucoma simplex group, and in 8% of the glaucoma capsulare group. No serious local or systemic side-effects were observed.
97例原发性开角型青光眼且眼压高于22毫米汞柱的患者共180只眼，使用马来酸噻吗洛尔治疗超过3年。其中130只眼为单纯性青光眼，50只眼为囊膜性青光眼。以马来酸噻吗洛尔作为唯一药物治疗3年后，单纯性青光眼组33%的患者眼压得到控制，囊膜性青光眼组则为8%。未观察到严重的局部或全身副作用。
