Jackson G, Korts D, Hanbury R, Sturiano V, Wolpert L, Cohen M, Stimmel B
Am J Drug Alcohol Abuse. 1982;9(1):69-76. doi: 10.3109/00952998209002611.
Alcohol use among methadone maintenance treatment program (MMTP) patients is substantial and a frequent impression is that addicts accelerate their consumption once in MMTP. This study reports an attempt to more clearly define alcohol consumption in opioid dependence as well as changes associated with methadone maintenance therapy. Two-day alcohol consumption (2-day EtOH) data were collected initially and quarterly on participants in a randomized controlled trial of intervention for alcoholism. Blood alcohol levels (BAL) were also determined. 17% of the participants were classified as active alcoholics (AA) and 8% as inactive alcoholics (IA). Two-day EtOH and BAL were significantly higher for AA than AI and nonalcoholics (NA, and AI higher than NA. Two-day EtOH decreased significantly over time for AA, AI, and NA. These findings indicate that AA among narcotic addicts and those on MMTP consume large quantities of EtOH but that consumption decreases with time on MMTP. The results, in confirmation of the work of others, suggest that entry and participation in MMTP has a broader effect than just on the use of narcotic drugs.
美沙酮维持治疗项目(MMTP)患者中的酒精使用情况较为普遍,人们常有的一种印象是,成瘾者一旦进入MMTP,饮酒量就会增加。本研究报告了一项旨在更清晰地界定阿片类药物依赖者的酒精消费情况以及与美沙酮维持治疗相关变化的尝试。最初以及每季度收集参加酒精中毒干预随机对照试验的参与者的两日酒精消费量(2日乙醇量)数据。还测定了血液酒精水平(BAL)。17%的参与者被归类为活跃酗酒者(AA),8%为非活跃酗酒者(IA)。AA的两日乙醇量和BAL显著高于IA和非酗酒者(NA),IA高于NA。AA、IA和NA的两日乙醇量随时间显著下降。这些发现表明,麻醉品成瘾者和接受MMTP治疗者中的AA饮酒量很大,但在MMTP治疗期间饮酒量会随时间减少。这些结果证实了其他人的研究成果,表明进入并参与MMTP的影响比仅对麻醉药品使用的影响更为广泛。