Oberhardt B J, Fogt E J, Clemens A H
Diabetes Care. 1982 May-Jun;5(3):213-7. doi: 10.2337/diacare.5.3.213.
An implantable glucose sensor must be free of baseline and sensitivity drift. To our knowledge, a drift-free glucose sensor with fast response time is not currently available. We are therefore proposing a miniature extracorporeal glucose sensor with access to the vascular system as a practical step toward implantation. This sensor could use existing technology to form the basis of a patient-wearable closed-loop system.
可植入式葡萄糖传感器必须无基线漂移和灵敏度漂移。据我们所知,目前尚无响应时间快且无漂移的葡萄糖传感器。因此,我们提议开发一种可接入血管系统的微型体外葡萄糖传感器,作为迈向植入式传感器的实际步骤。这种传感器可以利用现有技术,构成患者可穿戴闭环系统的基础。