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与多种癫痫发作类型相关的精神病理学增加:事实还是假象?

Increased psychopathology associated with multiple seizure types: fact or artifact?

作者信息

Hermann B P, Dikmen S, Wilensky A J

出版信息

Epilepsia. 1982 Dec;23(6):587-96. doi: 10.1111/j.1528-1157.1982.tb05073.x.

DOI:10.1111/j.1528-1157.1982.tb05073.x
PMID:7173126
Abstract

Previous investigations have reported that individuals with complex partial seizures (CPS) who also have experienced other types of seizures manifested more psychopathology than individuals with CPS who experienced only that type of seizure. These previous studies failed to match their seizure subgroups on important variables known to bear significant relationships with psychopathology, and the possibility that the previous results were due to artifact cannot be excluded. Thirty-three individuals with CPS only were compared to 34 individuals with both complex partial and secondarily generalized attacks (CPS/SG). The groups were closely matched on several potentially confounding variables and compared on Minnesota Multiphasic Personality Inventory (MMPI) measures of overall psychopathology, aggression, and psychosis. The CPS/SG group manifested significantly more psychopathology on all the MMPI measures and it was concluded that the multiple seizure type effect is real and robust. These findings were related to the larger epilepsy/ psychopathology literature.

摘要

先前的调查报道称,患有复杂部分性发作(CPS)且还经历过其他类型发作的个体,比仅经历该类型发作的CPS个体表现出更多的精神病理学症状。这些先前的研究未能在已知与精神病理学有显著关系的重要变量上对其发作亚组进行匹配,并且不能排除先前结果是由人为因素导致的可能性。将33名仅患有CPS的个体与34名患有复杂部分性发作和继发性全身性发作(CPS/SG)的个体进行了比较。两组在几个潜在的混杂变量上进行了密切匹配,并在明尼苏达多相人格问卷(MMPI)的总体精神病理学、攻击性和精神病性测量指标上进行了比较。CPS/SG组在所有MMPI测量指标上均表现出明显更多的精神病理学症状,得出的结论是多种发作类型的影响是真实且有力的。这些发现与更广泛的癫痫/精神病理学文献相关。

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Increased psychopathology associated with multiple seizure types: fact or artifact?与多种癫痫发作类型相关的精神病理学增加:事实还是假象?
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Depression in temporal lobe epilepsy: a review of prevalence, clinical features, and management considerations.颞叶癫痫中的抑郁:患病率、临床特征及管理考量综述
Epilepsy Res Treat. 2012;2012:809843. doi: 10.1155/2012/809843. Epub 2011 Dec 1.