海德果蝇Y染色体的遗传精细结构
Genetic fine structure of the Y chromosome of Drosophila hydei.
作者信息
Hackstein J H, Leoncini O, Beck H, Peelen G, Hennig W
出版信息
Genetics. 1982 Jun;101(2):257-77. doi: 10.1093/genetics/101.2.257.
Abstract
A genetic map of the Y chromosome of Drosophila hydei has been constructed from deletion/complementation experiments, with the aid of male sterile mutants of the Y chromosome. A central conclusion of our experiments is that not more than a single complementation group can be detected in each of the lampbrush loop forming sites. Additional complementation groups, functionally independent of lampbrush loops, reside between these loci. Six complementation groups have been defined by several methods of mapping. An additional ten complementation groups are indicated, but their exact definition requires further investigation. The "synthetic sterility" of mutations in these ten loci contributes to the difficulty in unequivocally establishing their individual boundaries. Mapping problems also arise from the instability of certain mutants.
摘要
利用果蝇海德氏果蝇Y染色体的雄性不育突变体，通过缺失/互补实验构建了其Y染色体的遗传图谱。我们实验的一个主要结论是，在每个灯刷环形成位点中，检测到的互补组不超过一个。功能上独立于灯刷环的其他互补组位于这些基因座之间。通过几种定位方法定义了六个互补组。另外还指出了十个互补组，但其确切定义需要进一步研究。这十个基因座中突变的“合成不育性”导致难以明确确定它们各自的边界。某些突变体的不稳定性也引发了定位问题。
相似文献
1
Genetic fine structure of the Y chromosome of Drosophila hydei.海德果蝇Y染色体的遗传精细结构
Genetics. 1982 Jun;101(2):257-77. doi: 10.1093/genetics/101.2.257.
2
DNA clones and RNA transcripts of four lampbrush loops from the Y chromosome of Drosophila hydei.海德氏果蝇Y染色体上四个灯刷环的DNA克隆和RNA转录本。
Cell. 1983 Jan;32(1):191-9. doi: 10.1016/0092-8674(83)90509-3.
3
Genetic and cytogenetic analysis of the "Th-Ps" region of the Y chromosome of Drosophila hydei: evidence for dual functions of the lampbrush loop-forming fertility genes?海德氏果蝇Y染色体“Th-Ps”区域的遗传与细胞遗传学分析：灯刷环形成育性基因具有双重功能的证据？
Mol Gen Genet. 1991 Jun;227(2):293-305. doi: 10.1007/BF00259683.
4
Differential staining of Y chromosomal lampbrush loops of Drosophila hydei.海德果蝇Y染色体灯刷环的差异染色
Chromosoma. 1981;83(5):679-84. doi: 10.1007/BF00328526.
5
"Hybrid" X--Y translocation chromosomes of Drosophila hydei and D. neohydei.海德果蝇和新海德果蝇的“杂种”X - Y易位染色体。
Chromosoma. 1982;86(4):491-508. doi: 10.1007/BF00330123.
6
Lampbrush loop-specific protein of Drosophila hydei.海德果蝇灯刷环特异性蛋白
Proc Natl Acad Sci U S A. 1984 Jun;81(11):3404-8. doi: 10.1073/pnas.81.11.3404.
7
Analysis of nuclear proteins in primary spermatocytes of Drosophila hydei: The correlation of nuclear proteins with the function of the Y chromosomal loops.海德果蝇初级精母细胞核蛋白分析：核蛋白与Y染色体环功能的相关性。
Chromosoma. 1981;84(1):67-86. doi: 10.1007/BF00293364.
8
Genes controlling chromosome activity; the role of genes blocking Y-lampbrush loop propagation.控制染色体活性的基因；阻止Y-灯刷环传播的基因的作用。
Chromosoma. 1975 Dec 10;53(3):231-41. doi: 10.1007/BF00329174.
9
Y chromosome loops in Drosophila melanogaster.黑腹果蝇中的Y染色体环
Genetics. 1988 Dec;120(4):1015-34. doi: 10.1093/genetics/120.4.1015.
10
Structure and function of Y chromosomal DNA. II. Analysis of lampbrush loop associated transcripts in nuclei of primary spermatocytes of Drosophila hydei by in situ hybridization using asymmetric RNA probes of four different families of repetitive DNA.Y染色体DNA的结构与功能。II. 使用四种不同重复DNA家族的不对称RNA探针，通过原位杂交分析海德氏果蝇初级精母细胞核中灯刷环相关转录本。
Chromosoma. 1988;96(2):159-70. doi: 10.1007/BF00331048.
引用本文的文献
1
as a Model System for Studying of the Evolution and Functional Specialization of the Y Chromosome.作为研究 Y 染色体进化和功能特化的模式系统。
Int J Mol Sci. 2022 Apr 10;23(8):4184. doi: 10.3390/ijms23084184.
2
Taming the giant within.驯服内心的巨人。
PLoS Genet. 2019 May 9;15(5):e1008098. doi: 10.1371/journal.pgen.1008098. eCollection 2019 May.
3
Satellite DNA-containing gigantic introns in a unique gene expression program during Drosophila spermatogenesis.卫星 DNA 富含巨型内含子的独特基因表达程序在果蝇精子发生过程中。
PLoS Genet. 2019 May 9;15(5):e1008028. doi: 10.1371/journal.pgen.1008028. eCollection 2019 May.
4
Spermatogenesis inDrosophila hydei: A genetic survey.海德果蝇的精子发生：一项遗传学调查。
Rouxs Arch Dev Biol. 1990 May;199(5):251-280. doi: 10.1007/BF01709505.
5
Autosomal control of lampbrush-loop formation during spermatogenesis in Drosophila hydei by a gene also affecting somatic sex determination.在海德果蝇精子发生过程中，灯刷环形成受常染色体控制，该控制由一个也影响体细胞性别决定的基因完成。
Rouxs Arch Dev Biol. 1987 Feb;196(2):119-123. doi: 10.1007/BF00402033.
6
Constructing balancer chromosomes for genetic screens in Drosophila hydei.构建果蝇 Hydei 遗传筛选的平衡染色体。
Theor Appl Genet. 1992 Apr;83(6-7):821-6. doi: 10.1007/BF00226703.
7
Lampbrush chromosome loop-specificity of transcript morphology in spermatocyte nuclei of Drosophila hydei.果蝇海德氏种精母细胞细胞核中灯刷染色体环特异性转录形态。
EMBO J. 1984 Dec 1;3(12):2845-9. doi: 10.1002/j.1460-2075.1984.tb02218.x.
8
Molecular cloning of microdissected lampbrush loop DNA sequences of Drosophila hydei.克隆秀丽隐杆线虫微切割灯刷环 DNA 序列。
EMBO J. 1983;2(10):1741-6. doi: 10.1002/j.1460-2075.1983.tb01651.x.
9
Mega-introns in the dynein gene DhDhc7(Y) on the heterochromatic Y chromosome give rise to the giant threads loops in primary spermatocytes of Drosophila hydei.异染色质Y染色体上动力蛋白基因DhDhc7(Y)中的超大内含子，导致海德氏果蝇初级精母细胞中出现巨大的线环。
Genetics. 2000 Feb;154(2):759-69. doi: 10.1093/genetics/154.2.759.
10
The Y chromosomal fertility factor Threads in Drosophila hydei harbors a functional gene encoding an axonemal dynein beta heavy chain protein.海德氏果蝇中的Y染色体生育因子Threads含有一个编码轴丝动力蛋白β重链蛋白的功能基因。
Genetics. 1998 Jul;149(3):1363-76. doi: 10.1093/genetics/149.3.1363.
本文引用的文献
1
Genetic Analysis of the Male Fertility Factors on the Y Chromosome of Drosophila Melanogaster.黑腹果蝇Y染色体上雄性育性因子的遗传分析
Genetics. 1960 Mar;45(3):257-74. doi: 10.1093/genetics/45.3.257.
2
SYNTHETIC STERILITY IN DROSOPHILA WILLISTONI.威氏果蝇的人工不育
Proc Natl Acad Sci U S A. 1960 Jun;46(6):832-3. doi: 10.1073/pnas.46.6.832.
3
[Phase specific function structure in spermatocyte nuclei of Drosophila melanogaster and their dependence of Y chromosomes].[黑腹果蝇精母细胞核中的阶段特异性功能结构及其对Y染色体的依赖性]
Chromosoma. 1961;12:676-716. doi: 10.1007/BF00328946.
4
[STRUCTURE-DIFFERENTIATION IN THE Y-CHROMOSOME OF DROSOPHILA HYDEI AND ITS RELATION TO GENE ACTIVITY. 3. SEQUENCE AND LOCALIZATION OF THE LOOP ORGANIZERS].[海德果蝇Y染色体的结构分化及其与基因活性的关系。3. 环组织者的序列与定位]
Chromosoma. 1965 Feb 16;16:222-48. doi: 10.1007/BF00320950.
5
Mutagenesis at a complex locus in Drosophila with the monofunctional alkylating agent, ethyl methanesulfonate.利用单功能烷基化剂甲磺酸乙酯在果蝇的一个复杂基因座上进行诱变。
Genetics. 1967 Dec;57(4):783-93. doi: 10.1093/genetics/57.4.783.
6
Relations between temperature sensitivity, amino acid replacements, and quaternary structure of mutant proteins.突变蛋白的温度敏感性、氨基酸替换与四级结构之间的关系。
Biochem Biophys Res Commun. 1966 Aug 23;24(4):577-83. doi: 10.1016/0006-291x(66)90360-3.
7
Synthetic lethality and semi-lethality among functionally related mutants of Drosophila melanfgaster.黑腹果蝇功能相关突变体间的合成致死和半致死现象。
Genetics. 1968 May;59(1):37-44. doi: 10.1093/genetics/59.1.37.
8
An analysis of white-mottled mutants in Drosophila hydei, with observations on X-Y exchanges in the male.海德果蝇白色斑驳突变体的分析，以及对雄性果蝇X-Y交换的观察。
Genetica. 1970;41(4):589-625. doi: 10.1007/BF00958938.
9
Temperature-sensitive mutations in Drosophila melanogaster.黑腹果蝇中的温度敏感突变
Science. 1970 Nov 13;170(3959):695-706. doi: 10.1126/science.170.3959.695.
10
Temperature-sensitive mutations in Drosophila melanogaster,I. Relative frequencies among gamma-ray and chemically induced sex-linked recessive lethals and semilethals.黑腹果蝇中的温度敏感突变，I. γ射线和化学诱导的性连锁隐性致死突变和半致死突变的相对频率。
Proc Natl Acad Sci U S A. 1967 Apr;57(4):907-12. doi: 10.1073/pnas.57.4.907.
Zotero 插件