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再谈平均杂合性。

Average heterozygosity revisited.

作者信息

Hedrick P W, Murray E

出版信息

Am J Hum Genet. 1978 Jul;30(4):377-82.

PMID:717400
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1685618/
Abstract

The estimate of heterozygosity and proportion of polymorphic loci for 33 red blood cell loci has been updated by the elimination of some loci of questionable status and the addition of data on 33 loci. The new figures for heterozygosity and proportion of polymorphic loci, .105 and .283, respectively, are based on 60 red blood cell loci of European origin populations. These values are less than those calculated by Lewontin in 1967, and furthermore they do not appear to be reaching an asymptote. At the present time, the red blood cell data and allozyme data for European populations have similar estimates of heterozygosity and proportion of polymorphic loci.

摘要

通过剔除一些状态存疑的位点并增加33个位点的数据，对33个红细胞位点的杂合度估计值和多态性位点比例进行了更新。杂合度和多态性位点比例的新数据分别为0.105和0.283，这些数据基于欧洲起源人群的60个红细胞位点。这些值低于1967年由Lewontin计算得出的值，而且它们似乎并未趋近于渐近线。目前，欧洲人群的红细胞数据和等位酶数据在杂合度和多态性位点比例的估计上较为相似。

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Theor Appl Genet. 1980 Jul;56(4):183-5. doi: 10.1007/BF00286681.

本文引用的文献

1
An estimate of average heterozygosity in man.人类平均杂合性的估计值。
Am J Hum Genet. 1967 Sep;19(5):681-5.
2
Evidence that enzyme polymorphisms are selectively neutral, but blood group polymorphisms are not.
Science. 1974 Mar 15;183(4129):1091-2. doi: 10.1126/science.183.4129.1091.
3
Average heterozygosity per locus in man: an estimate based on the incidence of enzyme polymorphisms.人类每个基因座的平均杂合性：基于酶多态性发生率的估计。
Ann Hum Genet. 1972 Jul;36(1):9-20. doi: 10.1111/j.1469-1809.1972.tb00578.x.
4
Genetic heterogeneity within electrophoretic "alleles" of xanthine dehydrogenase in Drosophila pseudoobscura.果蝇中黄嘌呤脱氢酶电泳“等位基因”内的遗传异质性。
Genetics. 1976 Nov;84(3):609-29. doi: 10.1093/genetics/84.3.609.

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