Dunphy E B, Dryja T P, Albert D M, Smith T R
Am J Ophthalmol. 1978 Nov;86(5):680-3. doi: 10.1016/0002-9394(78)90190-3.
A patient with spindle melanoma involving the iris and ciliary body refused enucleation at the time of diagnosis in 1933. The eye developed painful glaucoma 13 years later and was enucleated. Histopathologic examination indicated spread of the tumor intrasclerally and subconjunctivally. The patient is still alive without evidence of metastases, 32 years after enucleation and 45 years after initial diagnosis.
