Zakka K A, Foos R Y, Sulit H
Br J Ophthalmol. 1979 Nov;63(11):744-9. doi: 10.1136/bjo.63.11.744.
A case of metastatic tapioca melanoma of the iris in a 12-year-old girl is reported. The patient had heterochromia, a red painful eye, and was treated for iritis with secondary glaucoma. In the course of 5 months iris lesions with the clinical appearance of tapioca pudding developed, and biopsy disclosed a melanoma. The eye was immediately enucleated, and pathological examination showed a melanoma with predominantly epithelioid-type cells which had infiltrated the angle, the posterior chamber, and the surgical wounds. Conjunctival extension was noted 10 months after enucleation, and regional lymph node metastases were found 4 months later. Previously reported cases are reviewed and compared with the present case.
报告了一例12岁女孩的虹膜转移性木薯样黑色素瘤病例。该患者有虹膜异色症、眼红痛,曾因虹膜炎继发青光眼接受治疗。在5个月的病程中,出现了临床表现为木薯布丁样的虹膜病变,活检显示为黑色素瘤。患眼立即被摘除,病理检查显示为主要由上皮样细胞构成的黑色素瘤,已浸润房角、后房和手术创口。眼球摘除术后10个月发现结膜转移,4个月后发现区域淋巴结转移。对先前报道的病例进行了回顾并与本病例进行了比较。