电刺激诱导骨痂形成及其骨生成。

Electrical callus formation and its osteogenesis.

作者信息

Ohashi T

出版信息

Nihon Seikeigeka Gakkai Zasshi. 1982 Jul;56(7):615-33.

Abstract

Three different electric stimulation methods--direct current, electric Teflon film and PMLG piezoelectric film--could induce electrical osteogenesis around Donryu rat femur. The configuration of each type of electrical osteogenesis was different but the histological findings were essentially the same. 3H-thymidine autoradiographic studies were carried out on rat femurs stimulated by direct current to elucidate some mechanisms of electrical osteogensis. The results disclosed that the electric stimulation affected not only proliferation of osteoprogenitor cells from the periosteal cells but also differentiation of osteoprogenitor cells to osteoblasts and finally to osteocytes.

摘要

三种不同的电刺激方法——直流电、聚四氟乙烯膜电刺激和聚甲基丙烯酸甲酯-聚甲基丙烯酸缩水甘油酯（PMLG）压电膜电刺激——均可在唐鱼大鼠股骨周围诱导电致成骨。每种电致成骨的形态不同，但组织学结果基本相同。对直流电刺激的大鼠股骨进行了³H-胸腺嘧啶核苷放射自显影研究，以阐明电致成骨的一些机制。结果显示，电刺激不仅影响骨膜细胞来源的骨祖细胞的增殖，还影响骨祖细胞向成骨细胞以及最终向骨细胞的分化。