Watanabe T, Pukel C S, Takeyama H, Lloyd K O, Shiku H, Li L T, Travassos L R, Oettgen H F, Old L J
J Exp Med. 1982 Dec 1;156(6):1884-9. doi: 10.1084/jem.156.6.1884.
AH antigen, initially defined by an antibody present in a melanoma patient, is a cell surface antigen found on approximately 65% of melanoma cell lines. Absorption analysis indicates that AH is a differentiation antigen marking normal and malignant cells of neuroectodermal origin. The AH determinant has been found to be related to GD2 ganglioside.
AH抗原最初由一名黑色素瘤患者体内存在的一种抗体所定义,是一种在约65%的黑色素瘤细胞系中发现的细胞表面抗原。吸收分析表明,AH是一种标记神经外胚层来源的正常细胞和恶性细胞的分化抗原。已发现AH决定簇与GD2神经节苷脂有关。