血型的免疫化学研究。第四部分。根据抗 -I和抗 -i血清与血型A、B、H、Le a、Le b及前体物质相关的各种抗原的反应模式进行分组。
Immunochemical studies on blood groups. LIV. Classification of anti-I and anti-i sera into groups based on reactivity patterns with various antigens related to the blood group A,B,H, Le a, Le b and precursor substances.
作者信息
Feizi T, Kabat E A
出版信息
J Exp Med. 1972 Jun 1;135(6):1247-58. doi: 10.1084/jem.135.6.1247.
Abstract
Quantitative precipitin assays were carried out with eleven anti-I and five anti-i cold agglutinin sera. Their reaction patterns with precursor substances and with certain antigens related to the A, B, H, Le(a), and Le(b) substances revealed at least six types of I and four types of i specificity. All of the I and i determinants appear to be represented in varying amounts on that fraction of the ovarian cyst precursor substance OG which was precipitated by 20% ethanol (OG 20% 2X). Only some of these determinants can be detected in the first periodate oxidation stages of A, B, and H substances, in cow substances, and in hydatid cyst fluid.
摘要
用11份抗-I和5份抗-i冷凝集素血清进行了定量沉淀试验。它们与前体物质以及与某些与A、B、H、Le(a)和Le(b)物质相关的抗原的反应模式显示出至少6种I特异性类型和4种i特异性类型。所有的I和i决定簇似乎都以不同的量存在于卵巢囊肿前体物质OG的一部分中，该部分被20%乙醇沉淀（OG 20% 2X）。只有其中一些决定簇可以在A、B和H物质、牛物质以及包虫囊肿液的第一期高碘酸盐氧化阶段检测到。
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