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癌症局部热疗设备。

Equipment for local hyperthermia therapy of cancer.

作者信息

Babbs C F, Oleson J R, Pearce J A

出版信息

Med Instrum. 1982 Sep-Oct;16(5):245-8.

PMID:7176989
Abstract

Technology for local heat therapy of cancer is evolving rapidly at a number of technologically diverse and geographically scattered institutions and companies. No single technology is superior to others in all applications, and no single company, laboratory, or research group has all the answers. An ideal system would provide focused heating at depth in a predictable fashion, with little probability of generating undesired hot spots in normal tissues and little interference with monitoring equipment. Existing systems approximate this ideal to different degrees, depending on the anatomy and geometry of the tumor and its surrounding tissues. In the foregoing discussion the important problem of measuring temperatures in tumors and normal tissues has been slighted. At the present time, all thermometry is necessarily invasive, and there are limitations to the number of points at which temperatures can be measured utilizing percutaneously placed catheters as conduits for thermometers. However, further advances in the art, the science, and the technology of local heat therapy are likely to be forthcoming in the next few years from a diverse community of investigators and young companies who are following an interesting variety of approaches. Continued research and development in the spirit of constructive, rather than destructive, competition will certainly advance the field substantially--much to the benefit of patients. At present, however, clinical engineers should realize that hyperthermia therapy for cancer is still experimental. Despite the flurry of commercial activity, considerable caution should be exercised in the purchase and use of hyperthermia equipment.

摘要

癌症局部热疗技术正在许多技术多样、地理位置分散的机构和公司中迅速发展。在所有应用中,没有一种技术比其他技术更优越,也没有一家公司、实验室或研究团队能给出所有答案。理想的系统应以可预测的方式在深部提供聚焦加热,在正常组织中产生不期望的热点的可能性很小,并且对监测设备的干扰也很小。现有系统根据肿瘤及其周围组织的解剖结构和几何形状在不同程度上接近这一理想状态。在前面的讨论中,肿瘤和正常组织温度测量的重要问题被忽视了。目前,所有温度测量都必然是侵入性的,并且利用经皮放置的导管作为温度计的通道来测量温度的点数存在限制。然而,在未来几年,来自不同研究人员群体和年轻公司的各种有趣方法可能会在局部热疗的艺术、科学和技术方面取得进一步进展。本着建设性而非破坏性竞争的精神持续进行研发肯定会极大地推动该领域的发展——这对患者非常有益。然而,目前临床工程师应该认识到癌症热疗仍然处于实验阶段。尽管商业活动活跃,但在购买和使用热疗设备时应格外谨慎。

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