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癌症局部热疗设备。

Equipment for local hyperthermia therapy of cancer.

作者信息

Babbs C F, Oleson J R, Pearce J A

出版信息

Med Instrum. 1982 Sep-Oct;16(5):245-8.

PMID:7176989
Abstract

Technology for local heat therapy of cancer is evolving rapidly at a number of technologically diverse and geographically scattered institutions and companies. No single technology is superior to others in all applications, and no single company, laboratory, or research group has all the answers. An ideal system would provide focused heating at depth in a predictable fashion, with little probability of generating undesired hot spots in normal tissues and little interference with monitoring equipment. Existing systems approximate this ideal to different degrees, depending on the anatomy and geometry of the tumor and its surrounding tissues. In the foregoing discussion the important problem of measuring temperatures in tumors and normal tissues has been slighted. At the present time, all thermometry is necessarily invasive, and there are limitations to the number of points at which temperatures can be measured utilizing percutaneously placed catheters as conduits for thermometers. However, further advances in the art, the science, and the technology of local heat therapy are likely to be forthcoming in the next few years from a diverse community of investigators and young companies who are following an interesting variety of approaches. Continued research and development in the spirit of constructive, rather than destructive, competition will certainly advance the field substantially--much to the benefit of patients. At present, however, clinical engineers should realize that hyperthermia therapy for cancer is still experimental. Despite the flurry of commercial activity, considerable caution should be exercised in the purchase and use of hyperthermia equipment.

摘要

癌症局部热疗技术正在许多技术多样、地理位置分散的机构和公司中迅速发展。在所有应用中,没有一种技术比其他技术更优越,也没有一家公司、实验室或研究团队能给出所有答案。理想的系统应以可预测的方式在深部提供聚焦加热,在正常组织中产生不期望的热点的可能性很小,并且对监测设备的干扰也很小。现有系统根据肿瘤及其周围组织的解剖结构和几何形状在不同程度上接近这一理想状态。在前面的讨论中,肿瘤和正常组织温度测量的重要问题被忽视了。目前,所有温度测量都必然是侵入性的,并且利用经皮放置的导管作为温度计的通道来测量温度的点数存在限制。然而,在未来几年,来自不同研究人员群体和年轻公司的各种有趣方法可能会在局部热疗的艺术、科学和技术方面取得进一步进展。本着建设性而非破坏性竞争的精神持续进行研发肯定会极大地推动该领域的发展——这对患者非常有益。然而,目前临床工程师应该认识到癌症热疗仍然处于实验阶段。尽管商业活动活跃,但在购买和使用热疗设备时应格外谨慎。

相似文献

1
Equipment for local hyperthermia therapy of cancer.癌症局部热疗设备。
Med Instrum. 1982 Sep-Oct;16(5):245-8.
2
Assessment of current hyperthermia technology.当前热疗技术评估
Cancer Res. 1979 Jun;39(6 Pt 2):2313-24.
3
Hyperthermia in the treatment of cancer.热疗在癌症治疗中的应用
Br J Cancer Suppl. 1982 Mar;5:96-100.
4
Experimental studies of various heating procedures for clinical application of localized hyperthermia.用于局部热疗临床应用的各种加热程序的实验研究。
Prog Clin Biol Res. 1982;107:585-96.
5
Physical principles of local heat therapy for cancer.癌症局部热疗的物理原理
Med Instrum. 1981 Nov-Dec;15(6):367-73.
6
[Present clinical status of hyperthermia associated with radiotherapy (author's transl)].[放疗相关热疗的当前临床状况(作者译)]
Bull Cancer. 1981;68(3):261-7.
7
[Clinical trial of cancer therapy by radiation combined with hyperthermia].[放射联合热疗治疗癌症的临床试验]
Gan To Kagaku Ryoho. 1983 Apr;10(4 Pt 1):894-902.
8
Clinical experiences with combined hyperthermia and radiotherapy in the treatment of cancer.热疗与放疗联合治疗癌症的临床经验。
Prog Clin Biol Res. 1982;107:751-60.
9
Regarding: Rosenthal DI, Glatstein E. "We've Got a Treatment, but What's the Disease?" The Oncologist 1996;1.关于:罗森塔尔·迪、格拉茨坦·埃。《我们有了一种治疗方法,但疾病是什么?》,《肿瘤学家》1996年;第1期。
Oncologist. 1997;2(1):59-61.
10
Applications of microwave, ultrasound, and radiofrequency heating.
Natl Cancer Inst Monogr. 1982 Jun;61:447-56.

引用本文的文献

1
Computer-aided design and evaluation of novel catheters for conductive interstitial hyperthermia.
Med Biol Eng Comput. 1991 Jan;29(1):25-33. doi: 10.1007/BF02446292.
2
Droop: a rapidly computable descriptor of local minimum tissue temperature during conductive interstitial hyperthermia.下垂:传导性组织间热疗期间局部最低组织温度的一种快速可计算描述符。
Med Biol Eng Comput. 1992 May;30(3):333-42. doi: 10.1007/BF02446972.