Igarashi S, Koyama T, Shimosaka S, Uchibori M
No Shinkei Geka. 1982 Sep;10(9):961-6.
We reported three brothers with lumbar canal stenosis out of six brothers. The three brothers had undergone laminectomy of the lumbar spine. Two of the three who were operated had to undergo emergency operation because of acute onset of paraplegia and micturition disturbance. At surgery we found thick and hypertrophic lamina at stenotic portion of the lumbar spine in case 1 and case 2 and pseudospondylolysthesis in case 3. These three brothers were also found to have narrow cervical canal. Two of them underwent decompressive procedure for cervical spine after lumbar surgery and the rest had already undergone anterior fusion of cervical spine at another hospital. A sister of the six brothers was also demonstrated to have narrow cervical canal. These cases suggested that there is hereditary influence on the pathogenesis of the developmental lumbar canal stenosis. We could find only two reports on familial lumbar canal stenosis in English literature. Our familial cases are considered interesting in the following points. 1) Two of three cases necessitated emergency operation and no mass lesion such as herniated disc, tumor or vascular anomaly was found at surgery. 2) All three cases had narrow cervical canal in association with lumbar canal stenosis.
我们报告了六兄弟中有三兄弟患有腰椎管狭窄症。这三兄弟均接受了腰椎椎板切除术。其中接受手术的三人中有两人因急性截瘫和排尿障碍而不得不接受急诊手术。在手术中，我们发现病例1和病例2腰椎狭窄部位的椎板增厚且肥大，病例3存在假性椎体滑脱。还发现这三兄弟颈椎管狭窄。其中两人在腰椎手术后接受了颈椎减压手术，其余人已在另一家医院接受了颈椎前路融合术。这六兄弟中的一个姐妹也被证明存在颈椎管狭窄。这些病例表明，发育性腰椎管狭窄症的发病机制存在遗传影响。在英文文献中，我们仅能找到两篇关于家族性腰椎管狭窄症的报道。我们的家族性病例在以下几点上被认为很有趣。1）三例中有两例需要急诊手术，且手术中未发现诸如椎间盘突出、肿瘤或血管异常等占位性病变。2）所有三例均伴有腰椎管狭窄的颈椎管狭窄。
