Rupieper N, Montel H, Stöcker L
Anaesthesist. 1978 Oct;27(10):83-5.
The influence of carticaine on the formation of methaemoglobin was investigated in 22 patients undergoind spinal (n = 10) or epidural (n = 12) anaesthesia. Carticaine in a dose of 1,35 mg/kg, as used for spinal anaesthesia, did not influence the concentration of methaemoglobin. Carticaine in a dose of 5 mg/kg however, as used for epidural anaesthesia, increased the formation of methaemoglobin slightly at 30 min after injection. This increase is of little clinical importance since the upper limits of the normal range were not reached.
研究了卡替卡因对22例接受脊髓麻醉（n = 10）或硬膜外麻醉（n = 12）患者高铁血红蛋白形成的影响。用于脊髓麻醉的1.35 mg/kg剂量的卡替卡因对高铁血红蛋白浓度没有影响。然而，用于硬膜外麻醉的5 mg/kg剂量的卡替卡因在注射后30分钟时会轻微增加高铁血红蛋白的形成。由于未达到正常范围的上限，这种增加在临床上意义不大。
