Donchev N, Spasovski M, Krustev L, Nosko M, Beshevlieva M
Probl Khig. 1982;7:76-80.
The authors examined experimental albino rats, treated with low vinyl chloride doses via electronmicroscopic autoradiography by marking with thymidine H3. It was established that no blastic processes developed in liver with the low vinyl chloride doses used. THe authors found a certain inhibition of the plastic functions of hepatocytes, manifested by the diminished marking of thymidine H3 in the nuclei of hepatocytes and Kupffer cells, being of essential importance for an eventual development of the blastic processes in liver.
作者通过用氚标记的胸腺嘧啶核苷进行电子显微镜放射自显影,对经低剂量氯乙烯处理的实验性白化大鼠进行了研究。结果表明,在所使用的低剂量氯乙烯条件下,肝脏中未出现成胚过程。作者发现肝细胞的合成功能有一定抑制,表现为肝细胞和库普弗细胞核中氚标记的胸腺嘧啶核苷减少,这对于肝脏最终成胚过程的发展至关重要。