• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[低剂量氯乙烯处理的白化大鼠肝脏的组织放射自显影分析]

[Histoautoradiographic analysis of the liver of albino rats treated with low doses of vinyl chloride].

作者信息

Donchev N, Spasovski M, Krustev L, Nosko M, Beshevlieva M

出版信息

Probl Khig. 1982;7:76-80.

PMID:7178071
Abstract

The authors examined experimental albino rats, treated with low vinyl chloride doses via electronmicroscopic autoradiography by marking with thymidine H3. It was established that no blastic processes developed in liver with the low vinyl chloride doses used. THe authors found a certain inhibition of the plastic functions of hepatocytes, manifested by the diminished marking of thymidine H3 in the nuclei of hepatocytes and Kupffer cells, being of essential importance for an eventual development of the blastic processes in liver.

摘要

作者通过用氚标记的胸腺嘧啶核苷进行电子显微镜放射自显影,对经低剂量氯乙烯处理的实验性白化大鼠进行了研究。结果表明,在所使用的低剂量氯乙烯条件下,肝脏中未出现成胚过程。作者发现肝细胞的合成功能有一定抑制,表现为肝细胞和库普弗细胞核中氚标记的胸腺嘧啶核苷减少,这对于肝脏最终成胚过程的发展至关重要。

相似文献

1
[Histoautoradiographic analysis of the liver of albino rats treated with low doses of vinyl chloride].[低剂量氯乙烯处理的白化大鼠肝脏的组织放射自显影分析]
Probl Khig. 1982;7:76-80.
2
[Evaluation of vinyl chloride toxicity based on its metabolism].基于氯乙烯代谢的毒性评估
Med Pr. 1985;36(1):31-41.
3
Formation and repair of DNA adducts in vinyl chloride- and vinyl fluoride-induced carcinogenesis.氯乙烯和氟乙烯诱导致癌过程中DNA加合物的形成与修复
IARC Sci Publ. 1999(150):29-43.
4
Experimental studies on the chronic toxic effects of vinyl chloride in rats.氯乙烯对大鼠慢性毒性作用的实验研究
J Hyg Epidemiol Microbiol Immunol. 1980;24(3):285-94.
5
[Effect of vinyl chloride on function and structure of liver in rats (author's transl)].氯乙烯对大鼠肝脏功能和结构的影响(作者译)
Przegl Lek. 1979;36(9):673-7.
6
Modulation of halothane and vinyl chloride induced acute injury to liver endoplastic reticulum.氟烷和氯乙烯诱导的肝脏内质网急性损伤的调节作用
Panminerva Med. 1976 Sep-Oct;18(9-10):367-74.
7
One-year time-sequence inhalation toxicity study of vinyl chloride in rats. III. Morphological changes in the liver.大鼠氯乙烯一年期时间序列吸入毒性研究。III. 肝脏的形态学变化
Toxicology. 1979 Jun-Jul;13(2):143-54.
8
On the acute hepatotoxicity of inhaled vinyl chloride.
Acta Morphol Acad Sci Hung. 1981;29(2-3):221-6.
9
[Hygienic regulation of vinyl chloride].[氯乙烯的卫生规定]
Gig Sanit. 1981 Mar(3):74-6.
10
[DNA damages and changes of certain hepatic biochemical indexes in rats exposed to vinyl chloride monomer].[氯乙烯单体暴露大鼠的DNA损伤及某些肝脏生化指标变化]
Wei Sheng Yan Jiu. 2004 May;33(3):273-5.