Fujii T, Hirayama J, Kanai H, Handa K, Kusama S, Yano K, Hirano H, Takizawa M
Radioisotopes. 1982 Jun;31(6):290-6.
On intravenous administration of 201TlCl (74 MBq (2 mCi), initial transit of it through the heart as well as subsequent uptake by the chest were recorded in the supine position using a scintillation camera coupling to a small digital computer, and remaining the patient in the same position perfusion scintigram with 99mTc-macroaggregated albumin (MAA) or transmission scintigram with a point source of 99mTcO4- too. The radioactivity of total injected dose of 201Tl (T) was calculated from the entire region on the initial transit of the tracer bolus through the heart, and that of unilateral lung (L) was done from the anterior image of 201Tl on which isocount map of the perfusion image or transmission one was superimposed. By these procedures, the lung uptake ratio of 201Tl was calculated by ratio of L/T, and expressed as percentage per entire unilateral lung and mean value (%) per pixel. The average values of the lung uptake ratio in circulatory diseases were 4.0 +/- 1.2% in the right lung, 2.7 +/- 1.2% in the left lung, and in respiratory diseases 4.5 +/- 2.1% and 2.3 +/- 1.0%, respectively. This technique is useful to quantify the lung uptake of 201Tl on the lung scintigram with 201TlCl.
静脉注射201TlCl（74 MBq（2 mCi））后，使用与小型数字计算机相连的闪烁相机，在仰卧位记录其首次通过心脏的情况以及随后胸部的摄取情况，并让患者保持相同体位，同时用99mTc-大颗粒聚合白蛋白（MAA）进行灌注闪烁显像或用99mTcO4-点源进行透射闪烁显像。根据示踪剂团首次通过心脏时整个区域计算201Tl（T）总注射剂量的放射性，根据灌注图像或透射图像等计数图叠加在其上的201Tl前位图像计算单侧肺（L）的放射性。通过这些步骤，201Tl的肺摄取率通过L/T比值计算得出，并以每侧全肺的百分比和每像素的平均值（%）表示。循环系统疾病中右肺和左肺的肺摄取率平均值分别为4.0±1.2%和2.7±1.2%，呼吸系统疾病中分别为4.5±2.1%和2.3±1.0%。该技术有助于定量分析用201TlCl进行肺闪烁显像时201Tl在肺内的摄取情况。
