De Moor A, Van Den Hende C, Moens Y, Desmet P
Am J Vet Res. 1978 Oct;39(10):1624-6.
A long-lasting increase of the plasma bromide concentration was found in 25 horses after clinical halothane anesthesia. The plasma bromide concentration was significantly (P less than 0.005) increased at the end of anesthesia. In 18 horses, peak values were reached between 48 and 72 hours after anesthesia. Eighteen days after horses had been anesthetized, the plasma bromide concentration remained significantly (P less than 0.005) increased. Significant correlation was not found between the total dose of halothane and the plasma bromide concentration. In 1 horse reanesthetized with halothane 4 days after initial halothane anesthesia, the plasma bromide concentration increased to high concentrations.
在25匹马接受临床氟烷麻醉后，发现血浆溴化物浓度持续升高。麻醉结束时血浆溴化物浓度显著升高（P<0.005）。在18匹马中，麻醉后48至72小时达到峰值。马匹麻醉18天后，血浆溴化物浓度仍显著升高（P<0.005）。未发现氟烷总剂量与血浆溴化物浓度之间存在显著相关性。在首次氟烷麻醉4天后用氟烷再次麻醉的1匹马中，血浆溴化物浓度升至高浓度。
