Hackl A, Krispel F
Strahlentherapie. 1982 Oct;158(10):606-11.
The authors demonstrated by means of computed tomography that some problems are offered by the standardized method of primary radiotherapy in case of carcinomas of the cervix. Especially when a low-dose curietherapy is applied without dose monitor, a radiation exposure of bladder and rectum exceeding the tolerance limit or a underdosage in the target volume are possible due to variable positions of the uterus and different thicknesses of the uterus wall, above all in the region of the cervix. The rate of complications can also be increased by a false, eccentric position of the intra-uterine applicator if the latter does not follow the cervical canal. In nearly half of 61 patients with carcinomas of the cervix of stage I or III according to FIGO, computed tomography scanning showed a false position of the intra-uterine applicator probe. Besides the correction of the probe position, the problem can be solved by a dose reduction and use of shorter applicators or by a modified relation between brachytherapy and percutaneous therapy.
作者通过计算机断层扫描证明,在子宫颈癌的情况下,原发性放射治疗的标准化方法存在一些问题。特别是在未使用剂量监测器进行低剂量镭疗时,由于子宫位置可变和子宫壁厚度不同,尤其是在子宫颈区域,膀胱和直肠的辐射暴露可能超过耐受极限,或者靶体积内剂量不足。如果子宫内施源器未沿宫颈管放置,其错误的偏心位置也会增加并发症发生率。在国际妇产科联合会(FIGO)分期为I期或III期的61例子宫颈癌患者中,近一半患者的计算机断层扫描显示子宫内施源器探头位置错误。除了校正探头位置外,还可以通过降低剂量、使用更短的施源器或改变近距离放疗与经皮治疗之间的关系来解决这个问题。