Denev I, Kostov R, Vasilev I, Gruev A, Tonchev T
Vet Med Nauki. 1982;19(4):83-9.
Experiments were carried out with the preparation Nilsan (oxiclozanide + levamizal) in the treatment of sheep with Fasciola, Dictyocaulus, and Trichostrongylus infection. The trials involved a total of 2782 sheep on two sheep-breeding farms, constituting 15 flocks. The liveweight of the adult animals ranged from 40 to 60 kg, and that of the year-old female ones--from 40 to 45 kg. The daily ration on the two farms did not differ essentially from that offered to the animals in the past 2-3 years. It was found that at the rate of 22 to 28 cm3 per head Nilsan produced 76.67 to 96.67 percent effect against Paramphistomum infection, 100 percent effect against Dictyocaulus infection, 73.37 to 90.00 percent effect against Trichostrongylus infection, and 23.34 to 83.34 percent effect against Dicrocelium infection. The application of an ex tempore combination of oxiclozanide and levamizal to sheep at the rate of 24 cm3 per head produced 86.67 to 100 percent effect against Paramphistomum, 96.67 to 100 percent effect against Dictyocaulus, 86.67 to 96.67 percent effect against Trichostrongylus, and 46.67 to 86.67 percent effect against Dicrocelium. The experimental sheep produced 16.41 to 37.40 per cent more wool, 0.85 to 35.09 per cent more milk, and 8 to 12 per cent more weight gain.
用尼山（氯硝柳胺+左旋咪唑）制剂对感染肝片吸虫、网尾线虫和毛圆线虫的绵羊进行了治疗实验。试验涉及两个养羊场的2782只绵羊，共15个羊群。成年动物的体重在40至60千克之间，一岁母羊的体重在40至45千克之间。这两个农场的日粮与过去两三年给动物提供的日粮基本没有差别。结果发现，每头羊按22至28立方厘米的剂量使用尼山，对双口吸虫感染的疗效为76.67%至96.67%，对网尾线虫感染的疗效为100%，对毛圆线虫感染的疗效为73.37%至90.00%，对枝双腔吸虫感染的疗效为23.34%至83.34%。每头羊按24立方厘米的剂量给绵羊临时使用氯硝柳胺和左旋咪唑的合剂，对双口吸虫的疗效为86.67%至100%，对网尾线虫的疗效为96.67%至100%，对毛圆线虫的疗效为86.67%至96.67%，对枝双腔吸虫的疗效为46.67%至86.67%。实验绵羊的产毛量增加了16.41%至37.40%，产奶量增加了0.85%至35.09%，体重增加了8%至12%。
