van Schalkwyk P C, Geyser T L, Récio M, Erasmus F P
J S Afr Vet Assoc. 1979 Mar;50(1):31-5.
Anthelmintic trials were carried out to evaluate the efficacy of albendazole against helmi of 2,5 to 3,8 mg/kg administered orally, resulted in a 98,8 to 100% reduction of adult parasites of the genera Haemonchus, Ostertagia, Trichostrongylus, Nematodirus, Gaigeria, Oesophagostomum, Chabertia, Marshallagia and Cooperia. Against the immature stages of these genera, except for Marshallagia and Cooperia, which were not tested, a dose level of 2,5 to 3,8 mg/kg was 83,9-100% effective. Albendazole at 2,5 mg/kg was 99,0% effective against adult stages of Dictyocaulus; its activity at a dose of 3,8 mg/kg against the immature stages of D. filaria was 89,3%. In sheep naturally infested with Moniezia, 100% elimination was obtained at a dose level of 2,5 mg/kg. Dose levels of 3,8 mg/kg and higher were more than 76% effective against adult Fasciola hepatica, while a dose of 4,8 mg/kg was 63% effective against adult Fasciola gigantica.
进行了驱虫试验，以评估阿苯达唑对蠕虫的疗效。口服剂量为2.5至3.8毫克/千克，可使血矛线虫属、奥斯特他线虫属、毛圆线虫属、细颈线虫属、盖氏线虫属、食道口线虫属、夏伯特线虫属、马歇尔线虫属和古柏线虫属的成虫寄生虫减少98.8%至100%。对于这些属的未成熟阶段，除未测试的马歇尔线虫属和古柏线虫属外，2.5至3.8毫克/千克的剂量水平有效率为83.9% - 100%。2.5毫克/千克的阿苯达唑对网尾线虫成虫阶段的有效率为99.0%；其3.8毫克/千克剂量对丝状网尾线虫未成熟阶段的活性为89.3%。在自然感染莫尼茨绦虫的绵羊中，2.5毫克/千克的剂量水平可实现100%的清除。3.8毫克/千克及更高剂量水平对肝片形吸虫成虫的有效率超过76%，而4.8毫克/千克的剂量对巨片形吸虫成虫的有效率为63%。
