McManus K A, Brackbill Y, Woodward L, Doering P, Robinson D
Women Health. 1982 Spring;7(1):15-29. doi: 10.1300/J013v07n01_03.
This study investigated the amount of information that mothers have about the drugs to which they are exposed during pregnancy and childbirth as well as the correlates of this information, in particular perceived and actual control over life and health-related events. Subjects were 304 randomly chosen inpatients interviewed within 48 hours after childbirth. The results show that mothers know very little about the medications they took prenatally and even less about the medications they were administered during labor and delivery. Failing adequate information, a large number of mothers and babies were exposed to drugs with teratogenic or toxic potential. With but one exception, these drugs had not been approved by the F.D.A. for use in pregnancy, labor, and delivery. Scores on the Rotter Locus of Control Scale reliably predicted prenatal drug information.
本研究调查了母亲们对于她们在怀孕和分娩期间接触到的药物所掌握的信息量，以及这些信息的相关因素，特别是对生活和健康相关事件的感知控制和实际控制。研究对象是304名在分娩后48小时内随机选取的住院产妇。结果显示，母亲们对她们产前服用的药物了解甚少，对分娩期间使用的药物了解更少。由于缺乏足够的信息，大量母亲和婴儿接触到了具有致畸或毒性潜力的药物。除了一种药物外，这些药物均未获得美国食品药品监督管理局（F.D.A.）批准用于孕期、分娩期。Rotter控制点量表的得分能够可靠地预测产前药物信息。
