Gauthier M J, Bernard P, Aubert M
Ann Microbiol (Paris). 1978 Jul;129B(1):63-70.
A lipid antibiotic was extracted from whole cells of the marine diatom Chaetoceros lauderi (Ralfs) and roughly identified as an unsaturated fatty acid by thin layer chromatography. A number of Gram-positive terrestrial bacteria and several Gram-negative marine bacilli were sensitive to this antibiotic, whereas Gram-negative enteric bacteria were resistant. Solar irradiation led to its partial disappearance and to the production of more polar antibiotics with a stronger antibacterial activity. This observation is compared to similar data culled from literature, and its significance in a natural environment is discussed.
从海洋硅藻劳氏角毛藻(Chaetoceros lauderi (Ralfs))的全细胞中提取出一种脂质抗生素,并通过薄层色谱法初步鉴定为不饱和脂肪酸。多种革兰氏阳性陆生细菌和几种革兰氏阴性海洋杆菌对这种抗生素敏感,而革兰氏阴性肠道细菌则具有抗性。太阳辐射导致其部分消失,并产生了具有更强抗菌活性的极性更强的抗生素。将这一观察结果与从文献中收集的类似数据进行了比较,并讨论了其在自然环境中的意义。