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鸡蛋白过敏的临床与免疫学研究。III. 用交叉放射免疫电泳(CRIE)研究鸡蛋白中的过敏原。

A clinical and immunological study of allergy to hen's egg white. III. Allergens in hen's egg white studied by crossed radio-immunoelectrophoresis (CRIE).

作者信息

Langeland T

出版信息

Allergy. 1982 Oct;37(7):521-30. doi: 10.1111/j.1398-9995.1982.tb02335.x.

Abstract

Allergens in hen's egg white were studied in crossed radio-immunoelectrophoresis (CRIE). Specific IgE-antibodies against different proteins in the egg white were examined in sera from 70 atopic patients with clinical hypersensitivity, and RAST greater than or equal to 2 to egg white. Ovalbumin, ovomucoid and an unidentified protein, antigen 22, were classified as major allergens. Specific IgE-antibodies against 10 more proteins in hen's egg white were detected. IgE-antibodies against lysozyme could not be detected.

摘要

采用交叉放射免疫电泳(CRIE)研究了鸡蛋白中的变应原。检测了70例有临床过敏反应且对鸡蛋白的放射性变应原吸附试验(RAST)大于或等于2的特应性患者血清中针对鸡蛋白不同蛋白质的特异性IgE抗体。卵清蛋白、卵类粘蛋白和一种未鉴定的蛋白质抗原22被归类为主要变应原。还检测到了针对鸡蛋白中另外10种蛋白质的特异性IgE抗体。未检测到针对溶菌酶的IgE抗体。

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