Langeland T
Acta Derm Venereol Suppl (Stockh). 1985;114:109-12. doi: 10.2340/00015555114109112.
Clinical parameters of 84 egg-allergic children were recorded. The individual allergens in hen's egg white were studied by means of crossed radio-immunoelectrophoresis (CRIE). Thirteen of the proteins in the egg white were found to have given rise to IgE-antibody production in the egg-allergic children. The major allergens were identified as ovalbumin, ovomucoid and ovotransferrin. Pruritus and exacerbation of atopic dermatitis were the symptoms of egg allergy most frequently recorded. A clear association was found between egg allergy and atopic dermatitis and can be explained on basis of the relationship that seems to exist between atopic dermatitis and high levels of total IgE in serum. This relationship is discussed.
记录了84名鸡蛋过敏儿童的临床参数。通过交叉放射免疫电泳（CRIE）研究了鸡蛋白中的单个过敏原。发现蛋清中的13种蛋白质在鸡蛋过敏儿童中引发了IgE抗体产生。主要过敏原被鉴定为卵白蛋白、卵类粘蛋白和转铁蛋白。瘙痒和特应性皮炎加重是最常记录的鸡蛋过敏症状。发现鸡蛋过敏与特应性皮炎之间存在明显关联，这可以基于特应性皮炎与血清中总IgE高水平之间似乎存在的关系来解释。讨论了这种关系。
