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连续性动静脉血液滤过(CAVH)

[Continuous arteriovenous hemofiltration (CAVH)].

作者信息

Stokke T, Kramer P, Schrader J, Gröne H J, Burchardi H

出版信息

Anaesthesist. 1982 Oct;31(10):579-83.

PMID:7181083
Abstract

The continuous arteriovenous haemofiltration (CAVH) is a simple, safe, inexpensive and personnel-saving method for treatment of uremic patients. Since the introduction of the CAVH in 1977, far more than 200 patients have been treated by this method in our hospital. In the present paper the method and our experiences during the clinical application are presented. The haemofilter is placed in an extracorporal shunt between the A. and V. femoralis. Cannulation of these vessels is performed by means of a modified Seldinger technique using commercially available catheter. During haemofiltration, heparin is infused into the arterial blood line at a rate of 10 IU/kg . h. The filtrate is totally or partially replaced by nutrition solutions, enteral or parenteral, and by a potassium-free Ringer's lactate i.v. solution, according to the required fluid balance. In most cases the filtrate-substitution rate will be high enough to compensate renal failure, and thus conventional dialysis methods will not be necessary. Clinical experience to date allows the following conclusions: optimal control of water and electrolyte balance; unlimited parenteral nutrition, continuous fluid withdrawal better tolerated than intermittent withdrawal by means of dialysis; low risk of local bleeding with skilled puncture technique of the femoral vessels. Low dose continuous heparin administration into arterial blood line is sufficient for extracorporal anticoagulation. Saving of expenses: No investment costs for machines; specially trained dialysis personnel superfluous.

摘要

连续性动静脉血液滤过(CAVH)是一种治疗尿毒症患者的简单、安全、廉价且节省人力的方法。自1977年引入CAVH以来,我院已用该方法治疗了200多名患者。本文介绍了该方法及我们在临床应用中的经验。血液滤过器置于股动脉和股静脉之间的体外分流处。采用改良的Seldinger技术,使用市售导管对这些血管进行插管。在血液滤过过程中,肝素以10 IU/kg·h的速率注入动脉血路。根据所需的液体平衡,用肠内或肠外营养溶液以及无钾乳酸林格氏静脉溶液完全或部分替代滤液。在大多数情况下,滤液替代率将足够高以补偿肾衰竭,因此无需常规透析方法。迄今为止的临床经验可得出以下结论:能最佳地控制水和电解质平衡;可进行无限制的肠外营养,持续排液比通过透析间歇性排液更易耐受;熟练的股血管穿刺技术导致局部出血的风险低。向动脉血路中低剂量持续给予肝素足以进行体外抗凝。节省费用:无需机器投资成本;无需专门培训的透析人员。

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