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Good-bye CRRT, here comes SLED? ... not so fast!再见了连续性肾脏替代治疗(CRRT),间歇性延长每日血液透析(SLED)要来了?……没那么快!
Crit Care. 2012 Nov 5;16(6):167. doi: 10.1186/cc11651.
2
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[SLED v CRRT: the choice between a Rolls and a Ferrari?].[持续低效血液透析与连续性肾脏替代治疗:劳斯莱斯与法拉利之间的抉择?]
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本文引用的文献

1
Dialysis water and fluid purity: more than endotoxin.透析用水和液体纯度:不仅仅是内毒素。
Nephrol Dial Transplant. 2012 Nov;27(11):4010-21. doi: 10.1093/ndt/gfs306. Epub 2012 Jul 27.
2
Sustained low efficiency dialysis using a single-pass batch system in acute kidney injury - a randomized interventional trial: the REnal Replacement Therapy Study in Intensive Care Unit PatiEnts.急性肾损伤中使用单通道间歇系统进行持续低效透析——一项随机干预试验:重症监护病房患者的肾脏替代治疗研究
Crit Care. 2012 Jul 27;16(4):R140. doi: 10.1186/cc11445.
3
Why did dose trials fail?剂量试验为何失败?
Contrib Nephrol. 2011;174:222-231. doi: 10.1159/000329400. Epub 2011 Sep 9.
4
Clinical review: anticoagulation for continuous renal replacement therapy--heparin or citrate?临床综述:连续肾脏替代治疗的抗凝——肝素还是柠檬酸盐?
Crit Care. 2011 Jan 24;15(1):202. doi: 10.1186/cc9358.
5
Citrate anticoagulation for continuous venovenous hemofiltration.用于连续性静脉-静脉血液滤过的枸橼酸盐抗凝法。
Crit Care Med. 2009 Feb;37(2):545-52. doi: 10.1097/CCM.0b013e3181953c5e.
6
Enoxaparin vs. unfractionated heparin for anticoagulation during continuous veno-venous hemofiltration: a randomized controlled crossover study.依诺肝素与普通肝素用于持续静脉-静脉血液滤过抗凝的随机对照交叉研究
Intensive Care Med. 2007 Sep;33(9):1571-9. doi: 10.1007/s00134-007-0719-7. Epub 2007 Jun 12.
7
Adding a dialysis dose to continuous hemofiltration increases survival in patients with acute renal failure.在连续性血液滤过基础上增加透析剂量可提高急性肾衰竭患者的生存率。
Kidney Int. 2006 Oct;70(7):1312-7. doi: 10.1038/sj.ki.5001705. Epub 2006 Jul 19.
8
Regional citrate versus systemic heparin anticoagulation for continuous renal replacement in critically ill patients.危重症患者连续性肾脏替代治疗中局部枸橼酸盐与全身肝素抗凝的比较
Kidney Int. 2005 Jun;67(6):2361-7. doi: 10.1111/j.1523-1755.2005.00342.x.
9
Efficacy and cardiovascular tolerability of extended dialysis in critically ill patients: a randomized controlled study.
Am J Kidney Dis. 2004 Feb;43(2):342-9. doi: 10.1053/j.ajkd.2003.10.021.
10
Citrate vs. heparin for anticoagulation in continuous venovenous hemofiltration: a prospective randomized study.枸橼酸盐与肝素用于连续性静脉-静脉血液滤过抗凝的前瞻性随机研究。
Intensive Care Med. 2004 Feb;30(2):260-265. doi: 10.1007/s00134-003-2047-x. Epub 2003 Nov 5.

再见了连续性肾脏替代治疗(CRRT),间歇性延长每日血液透析(SLED)要来了?……没那么快!

Good-bye CRRT, here comes SLED? ... not so fast!

作者信息

Joannidis Michael

出版信息

Crit Care. 2012 Nov 5;16(6):167. doi: 10.1186/cc11651.

DOI:10.1186/cc11651
PMID:23148709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3672559/
Abstract

In the continuing dispute about the superiority of either intermittent or continuous renal replacement therapy for the critically ill, hybrid methods such as sustained low-efficiency dialysis (SLED) combining the advantages of both modalities--that is, excellent hemodynamic stability and low costs--receive growing attention. The study by Schwenger and colleagues is the first randomized trial indicating that there may be no significant difference in survival at 90 days between patients treated with SLED as compared with those treated with continuous veno-venous hemofiltration.

摘要

在关于间歇性或连续性肾脏替代疗法对危重症患者谁更具优势的持续争论中,诸如持续低效透析(SLED)这种结合了两种模式优点(即出色的血流动力学稳定性和低成本)的混合方法受到越来越多的关注。施温格及其同事开展的这项研究是首个随机试验,表明接受SLED治疗的患者与接受连续性静脉-静脉血液滤过治疗的患者相比,90天生存率可能没有显著差异。