Doby J M, Deunff J
Ann Parasitol Hum Comp. 1982;57(5):497-505.
The authors, taking into consideration, on the one hand, numbers of larvae issued from human cases and respectively identified as Hypoderma bovis and H. lineatum (at least when the specific determination cannot be put in doubt), on the other hand, the comparative intensity of serological reactions obtained between sera of more than one hundred cases by them diagnosed, and antigens respectively prepared from H. bovis and H. lineatum first instar larvae, come to the conclusion that, in France at least, the most numerous cases have as agent the first of these two species. They discuss different hypothesis giving possible explanation of the observed differences of frequency. On account of this higher frequency of cases by H. bovis, and of the complete lacking, sometimes, of crossed reactions with H. lineatum, they think that, for all serological researchs of human hypodermatosis, antigens corresponding to the two species have to be used, when, nearly always, alone is used H. lineatum antigen, for reason of easiness in collecting larvae for its preparing.
作者一方面考虑到源自人类病例且分别鉴定为牛皮蝇和纹皮蝇的幼虫数量(至少在特定鉴定无疑义时),另一方面考虑到他们诊断的一百多例病例的血清与分别由牛皮蝇和纹皮蝇一龄幼虫制备的抗原之间获得的血清学反应的相对强度,得出结论:至少在法国,大多数病例的病原体是这两个物种中的前者。他们讨论了不同的假设,这些假设可能解释观察到的频率差异。鉴于牛皮蝇病例的频率较高,且有时与纹皮蝇完全没有交叉反应,他们认为,对于人类皮蝇病的所有血清学研究,由于制备抗原时收集纹皮蝇幼虫更容易,几乎总是仅使用纹皮蝇抗原,而实际上必须使用对应于这两个物种的抗原。