Moss A L
Ann Plast Surg. 1982 Nov;9(5):431-5. doi: 10.1097/00000637-198211000-00014.
We report a case of rhinocerebral mucormycosis associated with diabetic ketoacidosis. The features of this rare, fulminating, fungal infection were not appreciated because of ignorance about the condition. The typical features include continued drowsiness in spite of correction of the diabetic ketoacidosis, black ulcer of the palate, septum or turbinate, facial pain, and cellulitis with varying eye and neurological signs. The general aspects of the infection are discussed, emphasizing that the mainstay of treatment is correction of the underlying condition, surgical debridement, and intravenous amphotericin B. Awareness of the condition will enable early diagnosis and adequate treatment to ensure the best chance of survival.
我们报告一例与糖尿病酮症酸中毒相关的鼻脑毛霉菌病病例。由于对该疾病缺乏了解，这种罕见、暴发性真菌感染的特征未被认识到。典型特征包括尽管糖尿病酮症酸中毒已得到纠正仍持续嗜睡、腭部、鼻中隔或鼻甲出现黑色溃疡、面部疼痛以及伴有不同眼部和神经体征的蜂窝织炎。本文讨论了该感染的一般情况，强调治疗的主要方法是纠正基础疾病、手术清创以及静脉注射两性霉素B。对该疾病的认识将有助于早期诊断和充分治疗，以确保最佳的生存机会。
