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[考虑两种底物浓度的土霉素产生菌生长动力学模型]

[Growth kinetics model of the oxytetracycline producer taking into account the concentrations of 2 substrates].

作者信息

Biriukov V V, Orlova N V, Pushkina Z T, Shnaĭder L E

出版信息

Antibiotiki. 1978 Nov;23(11):965-70.

PMID:718147
Abstract

The effect of starch and ammonium sulphate on the growth of the oxytetracycline-producing organism was studied using the procedure of acute experiments. It was proposed to use a mathematical model for description of the dependences taking into account the possibility of limiting or suppressing the growth of the culture by any of the above substrates as dependent on their ratio in the medium. Satisfactory confirmity of the model to the experimental data was shown. It was noted that similar models may be successfully used for description of such dependences as curves with flat plateau in the region of the maximum which are often met in microbiological processes.

摘要

采用急性实验方法研究了淀粉和硫酸铵对产土霉素微生物生长的影响。考虑到上述任何一种底物在培养基中的比例可能会限制或抑制培养物的生长,建议使用数学模型来描述这种依赖性。结果表明该模型与实验数据具有良好的一致性。值得注意的是,类似的模型可成功用于描述在微生物过程中经常遇到的、在最大值区域具有平缓平台的曲线等此类依赖性。

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